Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSV | O60911 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368594 | 0.94 | ALDH1A1 (0.63) | ALDH1A1LMNAABCB1MAPTMEN1 | |
| SCHEMBL965943 | 0.94 | ALDH1A1 (0.63) | ALDH1A1LMNAABCB1MAPTMEN1 | |
| SCHEMBL750245 | 0.84 | CTSV (0.63) | ABCB1MAPTMEN1KMT2ACTSV | |
| Acetic Acid SCHEMBL9653816 | 0.83 | CTSV (0.59) | ALDH1A1LMNAABCB1MAPTMEN1 | |
| SCHEMBL21775128 | 0.82 | SMN1; SMN2 (0.65) | ALDH1A1LMNAABCB1MAPTMEN1 | |
| SCHEMBL5706611 | 0.82 | CTSV (0.53) | ABCB1MAPTMEN1KMT2ACTSV | |
| SCHEMBL751415 | 0.82 | KMT2A (0.62) | ALDH1A1LMNAABCB1MAPTMEN1 | |
| SCHEMBL750963 | 0.82 | CTSV (0.58) | ALDH1A1LMNAABCB1MAPTMEN1 | |
| SCHEMBL16004968 | 0.82 | ABCB1 (0.59) | LMNAABCB1MAPTMEN1KMT2A | |
| SCHEMBL9658186 | 0.82 | CTSV (0.58) | ALDH1A1LMNAABCB1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |