Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 2/20 | 0.31 |
| ▸ | GPR4 | P46093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792640 | 0.91 | CTSK (0.36) | CTSKFGFR4HCRTR1HCRTR2XDH | |
| Trifluoroacetic Acid SCHEMBL5794082 | 0.84 | CTSK (0.36) | CTSKFGFR4 | |
| Trifluoroacetic Acid SCHEMBL5791564 | 0.83 | CTSK (0.35) | CTSKFGFR4 | |
| SCHEMBL5792575 | 0.82 | CTSK (0.44) | CTSKFGFR4HCRTR1HCRTR2XDH | |
| Trifluoroacetic Acid SCHEMBL5791710 | 0.82 | CTSK (0.38) | CTSKFGFR4GPR4 | |
| SCHEMBL5791034 | 0.82 | CTSK (0.42) | CTSKFGFR4HCRTR1HCRTR2XDH | |
| Trifluoroacetic Acid SCHEMBL5791177 | 0.82 | CTSK (0.42) | CTSKHCRTR1HCRTR2 | |
| SCHEMBL5793393 | 0.80 | CTSK (0.41) | CTSKFGFR4HCRTR1HCRTR2XDH | |
| SCHEMBL5791444 | 0.79 | CTSK (0.40) | CTSKFGFR4HCRTR1HCRTR2XDH | |
| Trifluoroacetic Acid SCHEMBL5792598 | 0.79 | CTSK (0.48) | CTSKGPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |