Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | GPR4 | P46093 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791034 | 0.92 | CTSK (0.42) | CTSKFGFR4GPR4XDHOPRM1 | |
| SCHEMBL5793393 | 0.90 | CTSK (0.41) | CTSKFGFR4GPR4XDHOPRM1 | |
| SCHEMBL5791444 | 0.89 | CTSK (0.40) | CTSKFGFR4GPR4XDHOPRM1 | |
| SCHEMBL5794663 | 0.88 | CTSK (0.39) | CTSKFGFR4GPR4XDHOPRM1 | |
| SCHEMBL3320226 | 0.84 | CTSK (0.47) | CTSKFGFR4GPR4XDHHCRTR1 | |
| SCHEMBL5792640 | 0.82 | CTSK (0.36) | CTSKFGFR4GPR4XDHOPRM1 | |
| SCHEMBL5804672 | 0.82 | CTSK (0.36) | CTSKFGFR4GPR4XDHHCRTR1 | |
| SCHEMBL5794549 | 0.82 | CTSK (0.41) | CTSKGPR4CTSLCTSBCTSS | |
| SCHEMBL5791035 | 0.82 | CTSK (0.45) | CTSKFGFR4GPR4XDH | |
| SCHEMBL5795031 | 0.81 | CTSK (0.35) | CTSKFGFR4HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |