Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16710174 | 0.81 | CA1 (0.46) | CA1CA2CA9CA5AMAPK1 | |
| SCHEMBL10066891 | 0.80 | KMT2A (0.44) | CA1CA2CA9CA5AMAPK1 | |
| SCHEMBL9959034 | 0.79 | CYP19A1 (0.45) | CA1CA2CA9ALDH1A1CA12 | |
| SCHEMBL4204972 | 0.74 | CA2 (0.56) | CA1CA2CA9CA5AMAPK1 | |
| SCHEMBL17258983 | 0.74 | CA1 (0.56) | CA1CA2CA9CA5AMAPK1 | |
| SCHEMBL17545281 | 0.72 | CA1 (0.54) | CA1CA2CA9CA5AMAPK1 | |
| SCHEMBL21827134 | 0.69 | CA1 (0.41) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL6241031 | 0.69 | CA2 (0.60) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL27704938 | 0.69 | CA2 (0.60) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL31159508 | 0.68 | CES1 (0.56) | CA1CA2CA9CA5AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132049-A1 | TREATING CANCERS USING BET INHIBITORS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-06-23 | — | — | WO | disclosed |
| WO-2005089515-A9 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | BRIGHAM & WOMENS HOSPITAL (US) | 2006-01-26 | — | — | WO | disclosed |