SCHEMBL58050

SCHEMBL58050

O=C1C=CC(=O)N1c1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 1.00
TLR9 Q9NR96 2/20 0.70
FAAH O00519 1/20 0.52
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 2/20 0.47
HSP90AA1 P07900 1/20 0.47
PKM P14618 1/20 0.47
CCR6 P51684 1/20 0.47
ATM Q13315 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
CASP1 P29466 1/20 0.45
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376713 1.00 MGLL (1.00) MGLLTLR9FAAHMEN1KMT2A
SCHEMBL29377102 0.83 TLR9 (1.00) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL121404 0.83 TLR9 (1.00) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL2343843 0.83 MGLL (0.70) MGLLTLR9FAAHMAPT
SCHEMBL28883339 0.79 MGLL (0.66) MGLLTLR9FAAHKMT2A
SCHEMBL9172497 0.79 MGLL (0.66) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL10447685 0.78 MGLL (0.63) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL24034719 0.78 MGLL (0.62) MGLLTLR9MEN1KMT2AALDH1A1
SCHEMBL11211240 0.77 MGLL (0.63) MGLLMEN1KMT2AALDH1A1PKM
SCHEMBL6832688 0.76 TLR9 (0.76) MGLLTLR9FAAHALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1848 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276107-A1 HYDROGEL SYSTEMS AND METHODS FOR TREATING FISTULA AND OTHER INDICATIONS TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION (US) 2025-09-04 US claimed
US-12258705-B2 Non-solvent 2K polyurethane artificial leather composition, artificial leather prepared with same and preparation method thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-25 US claimed
CN-117924787-A Low-temperature thermal expansion microsphere and preparation method thereof 万华化学集团股份有限公司 2024-04-26 CN claimed
CN-115845754-A Expanded composite microsphere and preparation method and application thereof 万华化学集团股份有限公司 2023-03-28 CN claimed
CN-110418783-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-10-04 CN claimed
US-11421060-B2 Dope solution for preparing optical film and optical film using the same LG MMA CORP. (KR) 2022-08-23 US claimed
US-20220259798-A1 NON-SOLVENT 2K POLYURETHANE ARTIFICIAL LEATHER COMPOSITION, ARTIFICIAL LEATHER PREPARED WITH SAME AND PREPARATION METHOD THEREOF DOW GLOBAL TECHNOLOGIES LLC 2022-08-18 US claimed
CN-110198927-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-08-12 CN claimed
EP-3636634-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2022-06-22 EP claimed
CN-109071432-B Synthesis method of N-substituted maleimide by using solid acid catalyst 株式会社LG化学 2022-04-12 CN claimed
EP-0196872-A2 Molding composition containing functionalised thermoplastic rubber and method ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-10-08 EP claimed
EP-0194384-A1 Thermodynamically miscible polymer compostions ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-09-17 EP claimed
US-4605700-A OLEFIN-MALEIMIDE COPOLYMER AND ACRYLONITRILE-VINYL AROMATIC COPOLYMER BLEND HAVING A SINGLE GLASS TRANSITION TEMPERATURE; MOLDINGS ATLANTIC RICHFIELD COMPANY (US) 1986-08-12 US claimed
US-4588774-A MOLDING MATERIALS, MALEIMIDE MONOMER, GRAFTED SYNTHETIC RUBBERS ATLANTIC RICHFIELD COMPANY (US) 1986-05-13 US claimed
US-4497928-A Moldable polyblend containing poly(arylene sulfide) ATLANTIC RICHFIELD COMPANY (US) 1985-02-05 US claimed
US-4427820-A STYRENE, MALEIC ACID DERIVATIVE, EMULSION POLYMERIZATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-24 US claimed
EP-0031997-B1 POLYMERISATION PROCESS FOR PRODUCTION OF POLYMER MICROPARTICLES OF HIGH REFRACTIVE INDEX AND COATING COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-28 EP claimed
US-4303779-A Thermosetting imide resins from dihydrazide TECHNOCHEMIE GMBH-VERFAHRENSTECHNIK (DE) 1981-12-01 US claimed
EP-0031997-A1 Polymerisation process for production of polymer microparticles of high refractive index and coating compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-07-15 EP claimed
US-4205020-A USED FOR MACHINE CASINGS, PIPES, CRASH HELMETS AND TELEPHONES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-05-27 US claimed