Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | USP14 | P54578 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804051 | 0.90 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11NPC1 | |
| SCHEMBL5816404 | 0.90 | CYP2C19 (0.47) | DRD2DRD3HRH3MCHR1NPC1 | |
| SCHEMBL5806158 | 0.83 | GRIN1 (0.49) | DRD2DRD3HRH3NPC1CYP2C19 | |
| SCHEMBL5807254 | 0.80 | GRIN1 (0.47) | NPC1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5820709 | 0.80 | MAPT (0.47) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL5805633 | 0.78 | MAPT (0.53) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL15452733 | 0.76 | DRD2 (0.43) | DRD2DRD3HRH3KDM4EHPGD | |
| SCHEMBL5814608 | 0.74 | MAPK9 (0.43) | MAPK14MAPK13MAPK12MAPK11HPGD | |
| SCHEMBL5806904 | 0.74 | MAPK9 (0.43) | MAPK14MAPK13MAPK12MAPK11HPGD | |
| SCHEMBL5814956 | 0.72 | MAPK9 (0.42) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | disclosed |