Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805633 | 0.94 | MAPT (0.53) | MAPTKMT2APOLBMAPK8MAPK9 | |
| SCHEMBL5814608 | 0.81 | MAPK9 (0.43) | MAPK8MAPK9MAPK10MAPK14MAPK13 | |
| SCHEMBL5806904 | 0.81 | MAPK9 (0.43) | MAPK8MAPK9MAPK10MAPK14MAPK13 | |
| SCHEMBL5823381 | 0.81 | HTR6 (0.36) | MAPK8MAPK9MAPK10ALDH1A1MAPK14 | |
| SCHEMBL5814956 | 0.80 | MAPK9 (0.42) | MAPK8MAPK9MAPK10MAPK14MAPK13 | |
| SCHEMBL5805306 | 0.80 | DRD2 (0.44) | KMT2AALDH1A1MAPK14MEN1MAPK13 | |
| SCHEMBL4961478 | 0.76 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11RIPK3 | |
| Hydrochloric Acid SCHEMBL749696 | 0.75 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11RIPK3 | |
| SCHEMBL5804051 | 0.74 | MAPK14 (0.47) | ALDH1A1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL14387351 | 0.73 | POLB (0.40) | MAPTKMT2APOLBMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | disclosed |