Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL579883 | 0.85 | HTT (0.53) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL579444 | 0.85 | OPRM1 (0.60) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL580074 | 0.83 | OPRM1 (0.51) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL579849 | 0.82 | OPRM1 (0.53) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL580457 | 0.81 | OPRM1 (0.58) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL580054 | 0.80 | OPRM1 (0.55) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL579606 | 0.79 | OPRM1 (0.65) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL579469 | 0.78 | OPRM1 (0.67) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL579511 | 0.78 | OPRM1 (0.61) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL580267 | 0.78 | OPRM1 (0.50) | OPRM1OPRD1OPRK1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735268-B1 | OPIOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2012-02-15 | — | — | EP | claimed |