Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.39 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796966 | 0.91 | TACR1 (0.49) | TACR1MEN1KMT2ASLC16A3SLC16A1 | |
| SCHEMBL5821365 | 0.88 | TACR1 (0.46) | TACR1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL5822661 | 0.85 | SGMS2 (0.44) | TACR1MEN1KMT2ASLC16A3SLC16A1 | |
| SCHEMBL4705941 | 0.76 | TP53 (0.50) | MEN1KMT2A | |
| SCHEMBL4706712 | 0.74 | TP53 (0.52) | MEN1KMT2A | |
| SCHEMBL6071885 | 0.73 | ALDH1A1 (0.45) | — | |
| SCHEMBL4708294 | 0.73 | MEN1 (0.38) | TACR1MEN1KMT2ASLC16A3SLC16A1 | |
| SCHEMBL4637788 | 0.72 | ALDH1A1 (0.45) | TACR1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL4705917 | 0.71 | IDH1 (0.50) | TACR1MEN1KMT2A | |
| SCHEMBL5797524 | 0.71 | ALDH1A1 (0.50) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638944-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005000821-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-01-06 | — | — | WO | disclosed |