Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806598 | 1.00 | GRIA1 (0.53) | GRIA1CDK5CDK5R1DYRK1APRMT5 | |
| SCHEMBL6620367 | 0.90 | GRIA1 (0.53) | GRIA1CDK5CDK5R1DYRK1ACASP3 | |
| SCHEMBL6620368 | 0.90 | GRIA1 (0.53) | GRIA1CDK5CDK5R1DYRK1ACASP3 | |
| SCHEMBL7631937 | 0.81 | GRIA1 (0.56) | GRIA1HTR2AHTR2CHTR2B | |
| SCHEMBL7631933 | 0.81 | GRIA1 (0.56) | GRIA1HTR2AHTR2CHTR2B | |
| SCHEMBL3227142 | 0.79 | GRIA1 (0.60) | GRIA1HTR2AHTR2CHTR2B | |
| SCHEMBL8367563 | 0.77 | GRIA1 (0.52) | GRIA1CASP3CASP7ATMROCK2 | |
| SCHEMBL8314975 | 0.77 | GRIA1 (0.82) | GRIA1 | |
| SCHEMBL31562999 | 0.77 | GRIA1 (0.60) | GRIA1 | |
| SCHEMBL8367555 | 0.75 | GRIA1 (0.80) | GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034196-A1 | COMPOSITIONS FOR ENHANCING MEMORY AND METHODS THEREFOR | LIFELIKE BIOMATIC INC. (US) | 2006-03-30 | — | — | WO | claimed |
| EP-0839134-B1 | BENZOYL PIPERIDINES/PYRROLIDINES FOR ENHANCING SYNAPTIC RESPONSE | UNIV CALIFORNIA (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-0839134-A1 | BENZOYL PIPERIDINES/PYRROLIDINES FOR ENHANCING SYNAPTIC RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5650409-A | FOR IMPROVING MEMORY, OR TREATING DEPRESSION, ALCOHOLISM OR SCHIZOPHRENIA | CORTEX PHARMACEUTICALS, INC. (US) | 1997-07-22 | — | — | US | disclosed |
| WO-1996038414-A1 | BENZOYL PIPERIDINES/PYRROLIDINES FOR ENHANCING SYNAPTIC RESPONSE | CORTEX PHARMACEUTICALS, INC. (US) | 1996-12-05 | — | — | WO | disclosed |