SCHEMBL580662

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL510894	0.83	MAP4K4 (0.41)	KCNN4KCNA3KDM4EGRM4PDK2
	SCHEMBL19078741	0.77	GRM4 (0.41)	NPC1RAB9ASMN1; SMN2GRM4ALDH1A1
	SCHEMBL70574	0.75	L3MBTL1 (0.44)	NPC1RAB9AKCNN4KCNA3SMN1; SMN2
	SCHEMBL17276686	0.74	TRPA1 (0.43)	KCNN4KCNA3CYP1A2CYP2C19PDK2
	SCHEMBL27869499	0.74	L3MBTL1 (0.52)	NPC1MAPTRAB9AKDM4ECYP1A2
	SCHEMBL4784136	0.73	L3MBTL1 (0.60)	KDM4ECYP1A2CYP2C9CYP2C19SMN1; SMN2
	SCHEMBL18229954	0.72	KCNN4 (0.42)	MAPTRAB9AKCNN4KCNA3CYP1A2
	SCHEMBL19032085	0.71	SMN1; SMN2 (0.42)	NPC1MAPTRAB9APKMKDM4E
	SCHEMBL3826876	0.71	KCNN4 (0.33)	NPC1RAB9AKCNN4KCNA3CYP1A2
	SCHEMBL3327536	0.71	DHODH (0.50)	NPC1MAPTRAB9APKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.