Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | XBP1 | P17861 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 7/20 | 0.61 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183545 | 0.81 | KMT2A (0.66) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27671164 | 0.79 | KMT2A (0.63) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| SCHEMBL258450 | 0.79 | KMT2A (0.63) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| SCHEMBL5807015 | 0.79 | TDP1 (0.63) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| SCHEMBL258449 | 0.79 | TDP1 (0.63) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| SCHEMBL17988274 | 0.77 | KMT2A (0.78) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| SCHEMBL2681858 | 0.77 | KMT2A (0.78) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| SCHEMBL15200988 | 0.77 | LMNA (0.58) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| Nifuroxime SCHEMBL5025023 | 0.76 | LMNA (0.76) | KMT2ATDP1MEN1MAPTL3MBTL1 | |
| SCHEMBL15978028 | 0.76 | KMT2A (0.62) | KMT2ATDP1MEN1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |
| US-4698352-A | 4-oxo-1,4-dihydronicotinic acid derivatives, salts thereof, and antibacterial agents containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| US-4196291-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-04-01 | — | — | US | disclosed |
| US-4141978-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-02-27 | — | — | US | disclosed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4001411-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-04 | — | — | US | disclosed |