Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281710 | 0.77 | LMNA (0.35) | LMNA | |
| SCHEMBL2818755 | 0.77 | LMNA (0.35) | LMNA | |
| SCHEMBL2818757 | 0.77 | LMNA (0.35) | LMNA | |
| SCHEMBL11628941 | 0.76 | LMNA (0.34) | LMNA | |
| SCHEMBL11271781 | 0.74 | LMNA (0.33) | LMNA | |
| SCHEMBL7139417 | 0.72 | LMNA (0.32) | LMNA | |
| SCHEMBL168749 | 0.72 | LMNA (0.43) | LMNA | |
| SCHEMBL10923560 | 0.69 | GAA (0.32) | LMNA | |
| SCHEMBL10920707 | 0.67 | PPM1B (0.35) | — | |
| SCHEMBL13199372 | 0.66 | LMNA (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605582-A1 | PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE | THE UNIVERSITY OF ROCHESTER (US) | 1994-07-13 | — | — | EP | claimed |
| US-5233031-A | Antitumor, anticarcinogenic agents | UNIVERSITY OF ROCHESTER (US) | 1993-08-03 | — | — | US | claimed |
| WO-1993006120-A1 | PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE | UNIVERSITY OF ROCHESTER (US) | 1993-04-01 | — | — | WO | claimed |
| WO-2006037090-A2 | DRUG-PHOSPHATE CONJUGATES AS PRODRUGS | PURDUE RESEARCH FOUNDATION (US) | 2006-04-06 | — | — | WO | disclosed |
| EP-0605582-A1 | PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE | THE UNIVERSITY OF ROCHESTER (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0605582-A1 | PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE | THE UNIVERSITY OF ROCHESTER (US) | 1994-07-13 | — | — | EP | disclosed |
| US-5233031-A | Antitumor, anticarcinogenic agents | UNIVERSITY OF ROCHESTER (US) | 1993-08-03 | — | — | US | disclosed |
| US-5233031-A | Antitumor, anticarcinogenic agents | UNIVERSITY OF ROCHESTER (US) | 1993-08-03 | — | — | US | disclosed |
| WO-1993006120-A1 | PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE | UNIVERSITY OF ROCHESTER (US) | 1993-04-01 | — | — | WO | disclosed |
| WO-1993006120-A1 | PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE | UNIVERSITY OF ROCHESTER (US) | 1993-04-01 | — | — | WO | disclosed |