Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804949 | 1.00 | CA1 (0.56) | CA1CA2CA4CA7MAPT | |
| SCHEMBL14573795 | 0.85 | MAPT (0.68) | CA1CA2CA4CA7MAPT | |
| SCHEMBL8038875 | 0.85 | MEN1 (0.63) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL5808845 | 0.82 | CA1 (0.72) | CA1CA2CA4CA7MAPT | |
| SCHEMBL5808849 | 0.82 | CA1 (0.72) | CA1CA2CA4CA7MAPT | |
| SCHEMBL6846903 | 0.79 | MAPT (0.56) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL8028859 | 0.78 | KMT2A (0.56) | CA1CA2CA4CA7MAPT | |
| SCHEMBL8028857 | 0.78 | KMT2A (0.56) | CA1CA2CA4CA7MAPT | |
| SCHEMBL927020 | 0.78 | MAPT (0.55) | CA1CA2CA4CA7MAPT | |
| SCHEMBL10045756 | 0.78 | MAPT (0.55) | CA1CA2CA4CA7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |