Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028857 | 1.00 | KMT2A (0.56) | KMT2AMEN1RECQLALDH1A1KDM4E | |
| SCHEMBL8038875 | 0.92 | MEN1 (0.63) | KMT2AMEN1RECQLALDH1A1HTT | |
| SCHEMBL28144455 | 0.86 | KMT2A (0.53) | KMT2AMEN1RECQLALDH1A1KDM4E | |
| SCHEMBL979463 | 0.84 | ALDH1A1 (0.67) | KMT2AMEN1RECQLALDH1A1KDM4E | |
| SCHEMBL28273258 | 0.84 | AKR1C3 (0.61) | KMT2AMEN1RECQLALDH1A1KDM4E | |
| SCHEMBL12396535 | 0.81 | AKR1C3 (0.64) | KMT2AMEN1RECQLALDH1A1HTT | |
| SCHEMBL31352034 | 0.81 | AKR1C3 (0.64) | KMT2AMEN1RECQLALDH1A1HTT | |
| SCHEMBL28224152 | 0.81 | MEN1 (0.60) | KMT2AMEN1MAPTLMNA | |
| SCHEMBL6583591 | 0.80 | HTT (0.67) | KMT2AMEN1RECQLALDH1A1KDM4E | |
| SCHEMBL2710798 | 0.80 | HTT (0.67) | KMT2AMEN1RECQLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | claimed |
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | disclosed |