Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13492514 | 0.82 | — | — | |
| SCHEMBL5314434 | 0.74 | ASGR1 (0.31) | — | |
| SCHEMBL5806869 | 0.73 | MEN1 (0.33) | TSHRMEN1KMT2A | |
| SCHEMBL5312843 | 0.72 | — | — | |
| SCHEMBL20999579 | 0.70 | PRKCA (0.35) | TSHRPRKCAALDH1A1MEN1KMT2A | |
| SCHEMBL17696339 | 0.69 | TSHR (0.39) | TSHRPRKCAALDH1A1LMNAKMT2A | |
| SCHEMBL8368795 | 0.68 | TSHR (0.64) | HPGDTSHRALDH1A1LMNAMEN1 | |
| SCHEMBL16059320 | 0.68 | TSHR (0.64) | HPGDTSHRALDH1A1LMNAMEN1 | |
| SCHEMBL28914636 | 0.66 | SMN1; SMN2 (0.46) | HPGDTSHRALDH1A1LMNAMEN1 | |
| SCHEMBL5804097 | 0.66 | EPHX1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117800-A2 | NOVEL 3, 4-PROPYLENEDIOXYTHIOPHENE DERIVATIVES WITH PENDANT FUNCTIONAL GROUPS | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2006-11-09 | — | — | WO | disclosed |