Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10265246 | 0.76 | LMNA (0.50) | CA1CA2LMNASRCTLR2 | |
| SCHEMBL22011034 | 0.76 | CA1 (0.43) | CA1CA2LMNASRCTLR2 | |
| SCHEMBL6389981 | 0.75 | DYRK1A (0.34) | — | |
| SCHEMBL1293351 | 0.73 | CA1 (0.61) | CA1CA2LMNASRCTLR2 | |
| SCHEMBL29940732 | 0.73 | CA1 (0.45) | CA1CA2LMNASRCTLR2 | |
| SCHEMBL1806253 | 0.73 | CA1 (0.45) | CA1CA2LMNASRCTLR2 | |
| SCHEMBL5807282 | 0.72 | CA1 (0.39) | CA1CA2LMNASRCTLR2 | |
| SCHEMBL15330946 | 0.71 | CA1 (0.38) | CA1CA2LMNASRCTLR2 | |
| SCHEMBL25706407 | 0.70 | CA1 (0.43) | CA1CA2SRCTLR2ERN1 | |
| SCHEMBL3905460 | 0.70 | LMNA (0.40) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |