Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940732 | 0.82 | CA1 (0.45) | CA1CA2SRCNPC1RAB9A | |
| SCHEMBL1806253 | 0.82 | CA1 (0.45) | CA1CA2SRCNPC1RAB9A | |
| SCHEMBL640294 | 0.77 | ALDH1A1 (0.56) | SRCNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1303053 | 0.76 | CA1 (0.40) | CA1CA2SRCNPC1RAB9A | |
| SCHEMBL10265246 | 0.76 | LMNA (0.50) | CA1CA2SRCNPC1RAB9A | |
| SCHEMBL6389985 | 0.75 | SMN1; SMN2 (0.32) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6324 | 0.74 | LMNA (0.43) | CA1CA2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1293351 | 0.73 | CA1 (0.61) | CA1CA2SRCNPC1RAB9A | |
| SCHEMBL22011034 | 0.72 | CA1 (0.43) | CA1CA2SRCALDH1A1SMN1; SMN2 | |
| SCHEMBL5807275 | 0.72 | CA1 (0.39) | CA1CA2SRCNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |