Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5275991 | 0.92 | ATR (0.35) | SMYD2HCRTR2ATRSIGMAR1MEN1 | |
| SCHEMBL5800718 | 0.85 | ATR (0.36) | ATRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5273742 | 0.85 | NAMPT (0.35) | ATRSIGMAR1KDM4ECD274TMEM97 | |
| SCHEMBL5273313 | 0.84 | ATR (0.36) | ATRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5810881 | 0.82 | SMN1; SMN2 (0.37) | SMYD2KDM4ECHEK1ALDH1A1MAPT | |
| SCHEMBL5823987 | 0.80 | KMT2A (0.31) | ATRMEN1KMT2AMAPT | |
| SCHEMBL5275258 | 0.79 | ATR (0.34) | ATRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5279743 | 0.79 | ALDH1A1 (0.37) | ATRMEN1KMT2AKDM4ECHRM2 | |
| SCHEMBL5277443 | 0.78 | SMN1; SMN2 (0.34) | SMYD2KDM4EFYNCD274ALDH1A1 | |
| SCHEMBL5276249 | 0.77 | SMYD2 (0.33) | SMYD2KDM4ECD274CHEK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099091-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | disclosed |