Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272930 | 0.93 | SPHK2 (0.34) | KDM4EKISS1RSPHK2ALDH1A1HPGD | |
| SCHEMBL5810881 | 0.93 | SMN1; SMN2 (0.37) | SMYD2KDM4EKISS1RSPHK2HTR7 | |
| SCHEMBL5277443 | 0.91 | SMN1; SMN2 (0.34) | SMYD2KDM4EHTR7HTR1ASMN1; SMN2 | |
| SCHEMBL5280997 | 0.87 | CD274 (0.36) | ALDH1A1HPGDPDCD1CD274 | |
| SCHEMBL5801918 | 0.87 | P2RY12 (0.34) | HTR7CHEK1LMNACD274 | |
| SCHEMBL5803928 | 0.86 | MAOB (0.35) | PDCD1CD274 | |
| SCHEMBL5273043 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HPGDLMNA | |
| SCHEMBL5281205 | 0.86 | ACKR3 (0.32) | CHEK1 | |
| SCHEMBL5278178 | 0.86 | ALDH1A1 (0.35) | SPHK2ALDH1A1HPGD | |
| SCHEMBL4695511 | 0.85 | PDCD1 (0.34) | SMN1; SMN2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856048-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006098999-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | claimed |