Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807480 | 0.86 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL7933617 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL11344627 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL5805791 | 0.79 | MAPT (0.63) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL12115502 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL5806475 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL2987459 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL4136897 | 0.75 | PKM (0.71) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL8288721 | 0.74 | ALDH1A1 (0.84) | ALDH1A1HPGDHSD17B10TSHRPKM | |
| SCHEMBL8288609 | 0.74 | ALDH1A1 (0.84) | ALDH1A1HPGDHSD17B10TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |