Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599652 | 0.93 | ALDH1A1 (0.56) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL11569500 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL4365560 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL5283349 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL11533777 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL5286463 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL5282914 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL902477 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL5303316 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL9186379 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006098909-A1 | METHODS FOR PREPARING POLYESTER-BASED NANOCOMPOSITES | CYCLICS CORPORATION (US) | 2006-09-21 | — | — | WO | disclosed |
| US-5576273-A | EXTREME PRESSURE, ALKYLENEBISDITHIOCARBAMATE, SYNERGISTIC | R.T. VANDERBILT COMPANY, INC. (US) | 1996-11-19 | — | — | US | disclosed |