SCHEMBL5807749

SCHEMBL5807749

C=CCc1c(C)nc(N)nc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
KDM4E B2RXH2 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 2/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CDC7 O00311 1/20 0.39
DBF4 Q9UBU7 1/20 0.39
ALDH1A1 P00352 3/20 0.36
PDE4B Q07343 3/20 0.36
PDE4D Q08499 3/20 0.36
MAPK1 P28482 2/20 0.36
RXRA P19793 2/20 0.36
NR4A2 P43354 2/20 0.36
HPGD P15428 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3800226 0.86 NPSR1 (0.38) NPSR1CDC7DBF4MAPT
SCHEMBL9284251 0.86 NPSR1 (0.55) NPSR1KDM4ESMN1; SMN2GAATSHR
SCHEMBL1034284 0.81 NPSR1 (0.35) NPSR1CDC7DBF4MAPT
SCHEMBL9287278 0.78 NPSR1 (0.51) NPSR1KDM4ESMN1; SMN2GAATSHR
SCHEMBL15508427 0.76 NPSR1 (0.46) NPSR1KDM4ESMN1; SMN2GAATSHR
SCHEMBL14270034 0.76 TLR8 (0.47) KDM4EALDH1A1MAPK1MAPTPOLB
SCHEMBL15429584 0.75 NPSR1 (0.45) NPSR1KDM4ESMN1; SMN2GAATSHR
SCHEMBL1684911 0.75 TLR8 (0.44) KDM4EALDH1A1
SCHEMBL4763149 0.74 KDM4E (0.38) NPSR1KDM4ESMN1; SMN2GAATSHR
SCHEMBL7029592 0.72 KDM4E (0.38) NPSR1KDM4ESMN1; SMN2GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114410234-B Halogen-free flame-retardant acetate-like fabric adhesive tape and preparation method thereof 苏州明钰轩纺织科技有限公司 2023-03-24 CN disclosed
CN-114410234-A Halogen-free flame-retardant acetate-like fabric adhesive tape and preparation method thereof 苏州明钰轩纺织科技有限公司 2022-04-29 CN disclosed
WO-2006069096-A1 SILANOL DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE PHARMACYCLICS, INC. (US) 2006-06-29 WO disclosed