Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434799 | 0.83 | TLR9 (0.47) | TLR9TLR8TLR7KDRPDE4A | |
| SCHEMBL17010347 | 0.82 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8840880 | 0.81 | PDE4A (0.67) | PDE4AKDM4EALDH1A1MAPTTHRB | |
| SCHEMBL16569388 | 0.81 | KDR (0.67) | TLR9TLR8TLR7KDRKDM4E | |
| SCHEMBL28032868 | 0.78 | KDR (0.55) | TLR9TLR8TLR7KDRPDE4A | |
| SCHEMBL30602130 | 0.78 | TLR7 (1.00) | TLR9TLR8TLR7 | |
| SCHEMBL27927388 | 0.74 | CYP1A2 (0.59) | KDM4EMAPTDYRK1ATDP1CYP3A4 | |
| SCHEMBL26260066 | 0.73 | HIF1A (0.43) | TLR9TLR8TLR7KDRKDM4E | |
| SCHEMBL29123104 | 0.73 | PDE4A (0.48) | PDE4AKDM4EALDH1A1MAPTTHRB | |
| SCHEMBL16541896 | 0.73 | PDE4A (0.57) | PDE4AKDM4EALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006026754-A9 | BICYCLIC HETEROARYL PDE4B INHIBITORS | PLEXXIKON INC (US) | 2006-04-20 | — | — | WO | disclosed |