Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133418 | 0.85 | HCRTR1 (0.55) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| SCHEMBL16672822 | 0.83 | HCRTR1 (0.54) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| SCHEMBL28840677 | 0.83 | HCRTR1 (0.54) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| SCHEMBL28394305 | 0.83 | ALDH1A1 (0.45) | L3MBTL1GLAMEN1KMT2AMAPT | |
| SCHEMBL9715756 | 0.83 | MEN1 (0.52) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| SCHEMBL14333370 | 0.82 | HCRTR1 (0.60) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| SCHEMBL124831 | 0.82 | ALDH1A1 (0.65) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| Benzene SCHEMBL27314454 | 0.82 | ALDH1A1 (0.65) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| SCHEMBL31568833 | 0.81 | KDM4E (0.53) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL27723974 | 0.81 | SGMS2 (0.59) | L3MBTL1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447646-B | A kind of method complete synthesis for natural product Moracin M | 中科院广州化学有限公司 | 2016-08-31 | — | — | CN | disclosed |
| WO-2006014484-A2 | METHODS AND DEVICES FOR THE TREATMENT OF OCULAR CONDITIONS | SURMODICS, INC. (US) | 2006-02-09 | — | — | WO | disclosed |