Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Nitrophenol SCHEMBL28636238 | 0.88 | HSD17B10 (0.54) | ALDH1A1MAPTHTTPTGS2ACHE | |
| P-Nitrophenol SCHEMBL11205589 | 0.86 | TSHR (0.53) | ALDH1A1MAPTHTTPTGS2ACHE | |
| P-Nitrophenol SCHEMBL28573812 | 0.86 | HSD17B10 (0.52) | ALDH1A1MAPTHTTPTGS2ACHE | |
| 1-Hydroxy-4-Ethoxybenzene SCHEMBL9671493 | 0.84 | PTGS2 (0.69) | ALDH1A1MAPTPTGS2ACHEBCL9 | |
| P-Nitrophenol SCHEMBL1115712 | 0.83 | HSD17B10 (0.58) | ALDH1A1MAPTHTTPTGS2ACHE | |
| P-Nitrophenol SCHEMBL1839 | 0.83 | CES1 (0.58) | ALDH1A1MAPTHTTPTGS2ACHE | |
| P-Nitrophenol SCHEMBL11048842 | 0.83 | CES1 (0.58) | ALDH1A1MAPTHTTPTGS2ACHE | |
| P-Nitrophenol SCHEMBL29806213 | 0.83 | CES1 (0.58) | ALDH1A1MAPTHTTPTGS2ACHE | |
| P-Nitrophenol SCHEMBL29016446 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTACHEBCL9 | |
| P-Nitrophenol SCHEMBL27858985 | 0.81 | PTGS1 (0.55) | ALDH1A1MAPTHTTPTGS2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006035459-A1 | AN IMPROVED PROCESS FOR THE PRODUCTION OF DERIVATIVES OF THIOZOLIDINEDIONES AND THEIR PRECURSORS | MOREPEN LABORATORIES LIMITED (IN) | 2006-04-06 | — | — | WO | disclosed |
| EP-0335274-B1 | Formation of nitrophenyl ethers from polyols and nitroanisoles | DOW CHEMICAL CO (US) | 1996-03-13 | — | — | EP | disclosed |
| US-4980161-A | APPLYING ANIMAL INTERFERON | SELA ILAN (IL) | 1990-12-25 | — | — | US | disclosed |
| US-4960950-A | Formation of nitrophenyl ethers from polyols and nitroanisoles | THE DOW CHEMICAL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0335274-A2 | Formation of nitrophenyl ethers from polyols and nitroanisoles | THE DOW CHEMICAL COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |