Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808299 | 1.00 | P2RX3 (0.46) | P2RX3KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5808511 | 0.86 | P2RX3 (0.48) | P2RX3KDM4EGAAALDH1A1MAPT | |
| SCHEMBL5808519 | 0.86 | P2RX3 (0.48) | P2RX3KDM4EGAAALDH1A1MAPT | |
| SCHEMBL5814023 | 0.85 | P2RX3 (0.47) | P2RX3KDM4EGAAALDH1A1MAPT | |
| SCHEMBL5814021 | 0.85 | P2RX3 (0.47) | P2RX3KDM4EGAAALDH1A1MAPT | |
| SCHEMBL5812055 | 0.85 | P2RX3 (0.45) | P2RX3KDM4EGAAALDH1A1MAPT | |
| SCHEMBL5807767 | 0.85 | P2RX3 (0.45) | P2RX3KDM4EGAAALDH1A1MAPT | |
| SCHEMBL5821567 | 0.83 | P2RX3 (0.48) | P2RX3KDM4EHTR1AGAAALDH1A1 | |
| SCHEMBL5821568 | 0.83 | P2RX3 (0.48) | P2RX3KDM4EHTR1AGAAALDH1A1 | |
| SCHEMBL5813399 | 0.82 | P2RX3 (0.49) | P2RX3KDM4ECYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | claimed |