Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813402 | 1.00 | P2RX3 (0.49) | P2RX3HDAC1MCL1BCL2MAPT | |
| SCHEMBL5808511 | 0.83 | P2RX3 (0.48) | P2RX3HDAC1MCL1MAPTGAA | |
| SCHEMBL5808519 | 0.83 | P2RX3 (0.48) | P2RX3HDAC1MCL1MAPTGAA | |
| SCHEMBL5814023 | 0.82 | P2RX3 (0.47) | P2RX3HDAC1MAPTGAAALDH1A1 | |
| SCHEMBL5814021 | 0.82 | P2RX3 (0.47) | P2RX3HDAC1MAPTGAAALDH1A1 | |
| SCHEMBL5813380 | 0.82 | P2RX3 (0.50) | P2RX3HDAC1MCL1MEN1KMT2A | |
| SCHEMBL5808295 | 0.82 | P2RX3 (0.46) | P2RX3HDAC1MCL1MAPTGAA | |
| SCHEMBL5808299 | 0.82 | P2RX3 (0.46) | P2RX3HDAC1MCL1MAPTGAA | |
| SCHEMBL5808572 | 0.82 | P2RX3 (0.50) | P2RX3HDAC1MCL1MEN1KMT2A | |
| SCHEMBL5799320 | 0.81 | HDAC1 (0.40) | P2RX3HDAC1LMNAHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | claimed |