Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553560 | 0.86 | TAAR1 (0.47) | PPARAPPARGEPHX1MAPTMEN1 | |
| SCHEMBL3961470 | 0.83 | FOLH1 (0.62) | HTR2AHTR2BPPARAHTR2CPPARG | |
| SCHEMBL5095202 | 0.83 | PPARA (0.64) | HTR2AHTR2BPPARAHTR2CPPARG | |
| SCHEMBL3961475 | 0.83 | FOLH1 (0.62) | HTR2AHTR2BPPARAHTR2CPPARG | |
| SCHEMBL3961471 | 0.83 | FOLH1 (0.62) | HTR2AHTR2BPPARAHTR2CPPARG | |
| SCHEMBL1816528 | 0.83 | HTR2A (0.56) | HTR2AHTR2BPPARAHTR2CPPARG | |
| Hydrochloric Acid SCHEMBL5095405 | 0.82 | PPARA (0.63) | HTR2AHTR2BPPARAHTR2CPPARG | |
| SCHEMBL3470487 | 0.81 | HTR2A (0.60) | HTR2AHTR2BPPARAHTR2CPPARG | |
| SCHEMBL31273982 | 0.81 | HTR2A (0.60) | HTR2AHTR2BPPARAHTR2CPPARG | |
| SCHEMBL13636190 | 0.80 | SLC1A1 (0.64) | HTR2AHTR2BPPARAHTR2CPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | disclosed |