Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.62 |
| ▸ | CPA1 | P15085 | 3/20 | 0.61 |
| ▸ | CPB1 | P15086 | 1/20 | 0.61 |
| ▸ | CPA3 | P15088 | 1/20 | 0.61 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.61 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961475 | 1.00 | FOLH1 (0.62) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL3961471 | 1.00 | FOLH1 (0.62) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL1816528 | 0.85 | HTR2A (0.56) | CPA1HTR2AHTR2BHTR2CPPARA | |
| SCHEMBL5095202 | 0.85 | PPARA (0.64) | HTR2AHTR2BHTR2CPPARAPPARG | |
| SCHEMBL3959231 | 0.85 | HTR2A (0.53) | FOLH1PIN1HTR2AHTR2BHTR2C | |
| SCHEMBL4608267 | 0.85 | HTR2A (0.53) | FOLH1PIN1HTR2AHTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL5095405 | 0.84 | PPARA (0.63) | HTR2AHTR2BHTR2CPPARAPPARG | |
| SCHEMBL1915318 | 0.83 | PPARA (0.49) | FOLH1CPA1PIN1HTR2AHTR2B | |
| SCHEMBL1915315 | 0.83 | PPARA (0.49) | FOLH1CPA1PIN1HTR2AHTR2B | |
| SCHEMBL5808951 | 0.83 | HTR2A (0.50) | CPA1HTR2AHTR2BHTR2CPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2004-10-28 | — | — | US | disclosed |
| US-6344449-B1 | HEADACHE AND MORPHINE DEPENDENCE | DR. KARL THOMAE GMBH (DE) | 2002-02-05 | — | — | US | disclosed |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | FOLH1 1512/4885CPA1 621/4885CPB1 1738/4885 |
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | FOLH1 900/4885CPA1 511/4885CPB1 1459/4885 |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | FOLH1 900/4885CPA1 511/4885CPB1 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.