Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 11/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.51 |
| ▸ | FER | P16591 | 7/20 | 0.48 |
| ▸ | STAT6 | P42226 | 2/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823998 | 0.85 | SYK (0.50) | SYKAURKBKCNH2ZAP70FER | |
| Ammonia Solution, Strong SCHEMBL5455420 | 0.77 | CSF1R (0.57) | SYKAURKBKCNH2ZAP70 | |
| SCHEMBL5808379 | 0.76 | ALOX15 (0.52) | — | |
| SCHEMBL8303878 | 0.75 | CSF1R (0.58) | SYKAURKBKCNH2ZAP70 | |
| SCHEMBL15161205 | 0.73 | SYK (0.66) | SYKAURKBKCNH2ZAP70STAT6 | |
| SCHEMBL2627318 | 0.72 | SYK (0.72) | SYKAURKBKCNH2ZAP70STAT6 | |
| SCHEMBL2714172 | 0.72 | SYK (0.57) | SYKAURKBKCNH2ZAP70FER | |
| SCHEMBL13624692 | 0.71 | SYK (0.67) | SYKAURKBKCNH2ZAP70STAT6 | |
| SCHEMBL29761550 | 0.70 | SYK (0.72) | SYKAURKBKCNH2ZAP70STAT6 | |
| SCHEMBL14659023 | 0.70 | SYK (0.72) | SYKAURKBKCNH2ZAP70STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673345-A1 | DERIVATIVES OF 3-AMINOCARBONYLQUINOLINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | GLAXO GROUP LIMITED (GB) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005030725-A1 | DERIVATIVES OF 3-AMINOCARBONYLQUINOLINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | GLAXO GROUP LIMITED (GB) | 2005-04-07 | — | — | WO | disclosed |