Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SDHB | P21912 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598084 | 0.86 | NR1H2 (0.54) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL2389145 | 0.83 | RXRA (0.75) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL2387435 | 0.82 | RXRA (0.67) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL2262382 | 0.81 | KDM4E (0.66) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL14944184 | 0.79 | RXRA (0.55) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL4905502 | 0.78 | RXRA (0.67) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL2264465 | 0.78 | KDM4E (0.57) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL14944222 | 0.77 | RXRA (0.51) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL2387427 | 0.75 | NR1H2 (0.65) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL2388586 | 0.75 | RXRA (0.76) | RXRANR1H2NR1H3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025979-A9 | MODULATORS OF NUCLEAR RECEPTORS | EXELIXIS INC (US) | 2006-04-20 | — | — | WO | claimed |