Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 8/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809689 | 0.90 | HDAC1 (0.43) | LMNAHDAC1L3MBTL1 | |
| SCHEMBL8260766 | 0.86 | MEN1 (0.39) | KMT2AMEN1MAPTCLK1DYRK1A | |
| SCHEMBL5817018 | 0.86 | MEN1 (0.40) | KMT2AMEN1MAPTCLK1DYRK1A | |
| SCHEMBL8260265 | 0.85 | MEN1 (0.38) | KMT2AMEN1MAPTCLK1DYRK1A | |
| SCHEMBL8259238 | 0.81 | LMNA (0.44) | LMNAHDAC1L3MBTL1 | |
| SCHEMBL3506115 | 0.77 | LMNA (0.41) | KMT2AMEN1LMNAHDAC1L3MBTL1 | |
| SCHEMBL5809384 | 0.74 | HDAC1 (0.39) | KMT2AMEN1LMNAHDAC1L3MBTL1 | |
| SCHEMBL17149258 | 0.72 | KMT2A (0.48) | KMT2AMEN1MAPTCLK1DYRK1A | |
| SCHEMBL15698872 | 0.71 | MAPT (0.52) | KMT2AMEN1MAPTCLK1DYRK1A | |
| SCHEMBL2895953 | 0.71 | MEN1 (0.64) | KMT2AMEN1MAPTCLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |