Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 5/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506115 | 0.91 | LMNA (0.41) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL5809222 | 0.86 | KMT2A (0.43) | MEN1MAPTKMT2ALMNAPTPN2 | |
| SCHEMBL5817018 | 0.81 | MEN1 (0.40) | MEN1MAPTKMT2ALMNAPTPN2 | |
| SCHEMBL8260265 | 0.80 | MEN1 (0.38) | MEN1MAPTKMT2ALMNAPOLB | |
| SCHEMBL8259037 | 0.80 | LMNA (0.41) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL5809384 | 0.78 | HDAC1 (0.39) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL8259238 | 0.77 | LMNA (0.44) | LMNAPOLBHDAC1L3MBTL1 | |
| SCHEMBL5809689 | 0.77 | HDAC1 (0.43) | LMNAHDAC1L3MBTL1 | |
| SCHEMBL3653587 | 0.73 | SMN1; SMN2 (0.45) | MEN1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL8258990 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |