Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837643 | 0.83 | ALDH1A1 (0.64) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL4948652 | 0.81 | L3MBTL1 (0.66) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL5808339 | 0.79 | L3MBTL1 (0.74) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL13692387 | 0.77 | L3MBTL1 (0.70) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL572624 | 0.77 | L3MBTL1 (0.70) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL13035827 | 0.76 | L3MBTL1 (0.64) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL13753404 | 0.75 | CYP26A1 (0.60) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL13076637 | 0.75 | L3MBTL1 (1.00) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL573429 | 0.75 | L3MBTL1 (0.68) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL13753594 | 0.75 | L3MBTL1 (0.62) | L3MBTL1LMNATSHRGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006091862-A2 | CYTOKINE INHIBITORS AND THEIR USE IN THERAPY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |