SCHEMBL5809372

SCHEMBL5809372

CCc1cccc2c1C=NNS2

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.35
GABRB2 P47870 4/20 0.35
TAAR1 Q96RJ0 2/20 0.32
HTR1A P08908 1/20 0.32
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27693760 0.62 TRPA1 (0.39)
SCHEMBL25765754 0.61
Ammonia Solution, Strong SCHEMBL28016359 0.61 TRPA1 (0.38)
SCHEMBL2590797 0.61 PDK2 (0.46) GABRA1GABRB2TAAR1HTR1ACRHBP
Iodide SCHEMBL2594068 0.58 PDK2 (0.43) GABRA1GABRB2TAAR1HTR1ACRHBP
SCHEMBL12142036 0.58 GABRA1 (0.48) GABRA1GABRB2CRHBPCRHR2
SCHEMBL25425763 0.57 GABRA1 (0.58) GABRA1GABRB2
SCHEMBL36294 0.57 GABRA1 (0.58) GABRA1GABRB2
SCHEMBL29390847 0.57 GABRA1 (0.58) GABRA1GABRB2
SCHEMBL599099 0.56 GABRA1 (0.57) GABRA1GABRB2TAAR1HTR1APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006034196-A1 COMPOSITIONS FOR ENHANCING MEMORY AND METHODS THEREFOR LIFELIKE BIOMATIC INC. (US) 2006-03-30 WO claimed
US-20060063707-A1 Compositions for enhancing memory and methods therefor LIFELIKE BIOMATIC, INC. (US) 2006-03-23 US claimed
WO-2006034196-A1 COMPOSITIONS FOR ENHANCING MEMORY AND METHODS THEREFOR LIFELIKE BIOMATIC INC. (US) 2006-03-30 WO disclosed
US-20060063707-A1 Compositions for enhancing memory and methods therefor LIFELIKE BIOMATIC, INC. (US) 2006-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063707-A1 Compositions for enhancing memory and methods therefor GRIN1, GRIN3A, GRIN2A GABRA1 34/4885GABRB2 44/4885TAAR1 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.