Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905217 | 0.89 | DRD2 (0.60) | DRD2DRD3LMNAHTR6CYP3A4 | |
| SCHEMBL5971750 | 0.87 | MAPT (0.55) | DRD2DRD3LMNAHTR6CYP3A4 | |
| SCHEMBL4787337 | 0.84 | DRD2 (0.44) | DRD2DRD3LMNAHTR1AADRA2A | |
| Fumaric Acid SCHEMBL3562688 | 0.82 | KDM4E (0.65) | DRD2DRD3LMNAHTR6CYP3A4 | |
| Fumaric Acid SCHEMBL3562685 | 0.82 | KDM4E (0.65) | DRD2DRD3LMNAHTR6CYP3A4 | |
| SCHEMBL5972036 | 0.81 | DRD2 (0.48) | DRD2DRD3HTR6CYP3A4HTR1A | |
| SCHEMBL5329365 | 0.80 | DRD2 (0.46) | DRD2DRD3LMNAHTR6CYP3A4 | |
| SCHEMBL5563082 | 0.80 | HTR2A (0.46) | DRD2DRD3LMNAHTR6CYP3A4 | |
| SCHEMBL1568098 | 0.79 | DRD2 (0.51) | DRD2DRD3LMNAHTR6HTR1A | |
| Hydrochloric Acid SCHEMBL1773502 | 0.78 | DRD2 (0.50) | DRD2LMNAHTR6CYP3A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027789-A1 | PROCESS FOR PRODUCING 11-[4-[2-(2-HYDROXYETHOXY)ETHYL]-1-PIPERAZINYL]DIBENZO[b,f][1,4]THIAZEPINE AND A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | JUBILANT ORGANOSYS LIMITED (IN) | 2006-03-16 | — | — | WO | disclosed |