Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14597900 | 0.89 | TRPV1 (0.73) | TRPV1NPC1RAB9AMAOBKDM4E | |
| SCHEMBL5494471 | 0.88 | MAOB (0.72) | TRPV1NPC1RAB9AMAOBKDM4E | |
| SCHEMBL5494974 | 0.88 | TRPM8 (0.74) | TRPM8KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL5494975 | 0.88 | TRPM8 (0.74) | TRPM8KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL29359315 | 0.81 | TRPV1 (0.67) | TRPV1NPC1RAB9AMAOBKDM4E | |
| SCHEMBL5494854 | 0.80 | MAOB (0.66) | TRPV1NPC1RAB9AMAOBKDM4E | |
| SCHEMBL5496910 | 0.77 | TRPM8 (0.71) | TRPM8KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL5496911 | 0.77 | TRPM8 (0.71) | TRPM8KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL5493158 | 0.76 | RAB9A (0.56) | TRPV1NPC1RAB9AMAOBKDM4E | |
| Ilepcimide SCHEMBL668328 | 0.75 | NPC1 (1.00) | TRPV1NPC1RAB9AMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103527-A1 | AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-05 | — | — | WO | disclosed |