Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142763 | 0.83 | LMNA (0.43) | MAPTLMNAMEN1KMT2ATSHR | |
| SCHEMBL5142799 | 0.79 | LMNA (0.39) | MAPTLMNAMEN1KMT2ATSHR | |
| SCHEMBL4620138 | 0.78 | LMNA (0.40) | LMNAMEN1KMT2ATSHR | |
| SCHEMBL5142689 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5145797 | 0.77 | TRPV1 (0.60) | — | |
| Hydrochloric Acid SCHEMBL5145801 | 0.77 | TRPV1 (0.60) | — | |
| SCHEMBL5142944 | 0.77 | — | — | |
| SCHEMBL14354959 | 0.77 | — | — | |
| SCHEMBL1013228 | 0.76 | AAK1 (0.47) | MAPTMEN1KMT2ATSHR | |
| SCHEMBL5141511 | 0.76 | MEN1 (0.35) | MAPTLMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089311-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2006-08-24 | — | — | WO | disclosed |