Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 6/20 | 0.61 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.60 |
| ▸ | DRD3 | P35462 | 4/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | HRH2 | P25021 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810188 | 1.00 | SCN4A (0.61) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| SCHEMBL3435133 | 1.00 | SCN4A (0.61) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| Bromide SCHEMBL4631988 | 0.99 | SCN4A (0.60) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| Bromide SCHEMBL1234856 | 0.99 | SCN4A (0.60) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| SCHEMBL3025573 | 0.87 | SCN4A (0.62) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| SCHEMBL8204692 | 0.85 | DRD3 (0.62) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| SCHEMBL1031126 | 0.85 | DRD3 (0.62) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| SCHEMBL1031127 | 0.85 | DRD3 (0.62) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| SCHEMBL31214169 | 0.84 | SCN4A (0.67) | SCN4ASCN3ASCN9ADRD3DRD2 | |
| Bromide SCHEMBL4103965 | 0.84 | DRD3 (0.61) | SCN4ASCN3ASCN9ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608286-B | Preparation method of high-purity pramipexole | 广东红珊瑚药业有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-112608286-A | Preparation method of high-purity pramipexole | 广东红珊瑚药业有限公司 | 2021-04-06 | — | — | CN | disclosed |
| WO-2006070349-A2 | NOVEL PROCESS FOR PREPARING PRAMIPEXOLE AND ITS OPTICAL ISOMERIC MIXTURE BY REDUCTION WITH SODIUM TRIACETOXYBOROHYDRIDE | CHEMAGIS LTD. (IL) | 2006-07-06 | — | — | WO | disclosed |
| US-20060148866-A1 | Novel process for preparing pramipexole and its optical isomeric mixture by reduction with sodium triacetoxyborohydride | CHEMAGIS LTD. (IL) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148866-A1 | Novel process for preparing pramipexole and its optical isomeric mixture by reduction with sodium triacetoxyborohydride | DPP4, ACE, ALDH1A2 | SCN4A 539/4885SCN3A 3801/4885SCN9A 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.