Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.38 |
| ▸ | HTR2A | P28223 | 11/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031885 | 0.86 | HTR2C (0.37) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6229841 | 0.85 | HTR2C (0.41) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL189124 | 0.80 | CDK4 (0.35) | HTR2CHTR2A | |
| SCHEMBL698157 | 0.79 | HTR2C (0.40) | HTR2CHTR2ATSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL694594 | 0.77 | CDK4 (0.41) | HTR2CHTR2ALMNAHTT | |
| SCHEMBL5814894 | 0.74 | CDK4 (0.44) | HTR2CHTR2ATSHRLMNAHTT | |
| SCHEMBL6228700 | 0.73 | CDK4 (0.35) | LMNA | |
| SCHEMBL6400236 | 0.72 | KMT2A (0.39) | HTR2CHTR2A | |
| SCHEMBL6231638 | 0.72 | HTR2C (0.33) | HTR2CHTR2A | |
| SCHEMBL16719793 | 0.72 | HTR2A (0.40) | HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |