Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.37 |
| ▸ | HTR2A | P28223 | 11/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229841 | 0.87 | HTR2C (0.41) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5810358 | 0.86 | HTR2C (0.38) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL698157 | 0.78 | HTR2C (0.40) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL189124 | 0.75 | CDK4 (0.35) | HTR2CHTR2A | |
| SCHEMBL694594 | 0.72 | CDK4 (0.41) | HTR2CHTR2A | |
| SCHEMBL6228700 | 0.72 | CDK4 (0.35) | — | |
| SCHEMBL6231638 | 0.71 | HTR2C (0.33) | HTR2CHTR2A | |
| SCHEMBL6400236 | 0.71 | KMT2A (0.39) | HTR2CHTR2A | |
| SCHEMBL16719793 | 0.71 | HTR2A (0.40) | HTR2CHTR2A | |
| SCHEMBL6229331 | 0.71 | GRM2 (0.34) | HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511477-B1 | Indole derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| EP-0511477-A1 | Indole derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |