Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 11/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5822557 | 0.99 | TRPC5 (0.38) | TRPC5IDH1PDE10APDE2APDE7A | |
| SCHEMBL5806451 | 0.91 | TRPC5 (0.45) | TRPC5IDH1BRD4 | |
| Hydrochloric Acid SCHEMBL5810454 | 0.90 | TRPC5 (0.44) | TRPC5IDH1BRD4 | |
| Hydrochloric Acid SCHEMBL5806513 | 0.86 | PPARG (0.42) | IDH1PDE10APDE2APDE7APDE11A | |
| Hydrochloric Acid SCHEMBL5809663 | 0.79 | ALDH1A1 (0.48) | TRPC5IDH1BRD4 | |
| SCHEMBL6250112 | 0.70 | DYRK1A (0.61) | — | |
| Hydrochloric Acid SCHEMBL6834656 | 0.69 | DYRK1A (0.60) | — | |
| SCHEMBL4233355 | 0.66 | POLB (0.51) | — | |
| SCHEMBL31020720 | 0.66 | TRPV1 (0.41) | TRPC5IDH1 | |
| SCHEMBL15730236 | 0.64 | PPARG (0.45) | IDH1PDE10APDE2APDE7APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050148-A2 | PROPARGYL TRIFLUOROMETHOXY AMINOBENZIMIDAZOLE DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-05-11 | — | — | WO | disclosed |