SCHEMBL5810449

SCHEMBL5810449

COCCn1c(C)c(C)c2ccnc(OC)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
RAB9A P51151 3/20 0.38
MEN1 O00255 2/20 0.38
NPC1 O15118 2/20 0.38
NR2F2 P24468 1/20 0.38
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
LMNA P02545 1/20 0.36
ALOX15 P16050 1/20 0.35
DYRK1A Q13627 4/20 0.34
TSHR P16473 2/20 0.34
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
HTR1A P08908 1/20 0.34
HTR2A P28223 1/20 0.34
HTR7 P34969 1/20 0.34
HTR6 P50406 1/20 0.34
NFATC1 O95644 1/20 0.34
GSK3B P49841 1/20 0.34
HASPIN Q8TF76 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5810813 0.99 KMT2A (0.37) KMT2ARAB9AMEN1NPC1NR2F2
SCHEMBL5806362 0.87 DYRK1A (0.46) KMT2AMEN1ALDH1A1TDP1LMNA
SCHEMBL5810011 0.85 KMT2A (0.35) KMT2ARAB9AMEN1NPC1NR2F2
SCHEMBL5809117 0.85 DYRK1A (0.35) RAB9ANPC1ALDH1A1DYRK1AHTR2A
Hydrochloric Acid SCHEMBL5806152 0.84 KMT2A (0.34) KMT2ARAB9AMEN1NPC1NR2F2
SCHEMBL5808673 0.84 DYRK1A (0.44) KMT2AMEN1DYRK1AHTR2AHASPIN
Hydrochloric Acid SCHEMBL5809596 0.83 KMT2A (0.34) KMT2ARAB9AMEN1NPC1NR2F2
SCHEMBL5806050 0.83 KMT2A (0.34) KMT2ARAB9AMEN1NPC1NR2F2
SCHEMBL1734869 0.83 DYRK1A (0.40) KMT2ARAB9AMEN1NPC1NR2F2
Hydrochloric Acid SCHEMBL5806405 0.82 MEN1 (0.33) KMT2ARAB9AMEN1NPC1NR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed