Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806362 | 0.88 | DYRK1A (0.46) | DYRK1AACSS2RPS6KA5MEN1KMT2A | |
| SCHEMBL5809117 | 0.86 | DYRK1A (0.35) | DYRK1AACSS2RPS6KA5HASPINMAOA | |
| SCHEMBL5807487 | 0.85 | LMNA (0.38) | DYRK1AACSS2RPS6KA5MEN1KMT2A | |
| SCHEMBL5810449 | 0.84 | KMT2A (0.38) | DYRK1AACSS2MEN1KMT2AHASPIN | |
| SCHEMBL5806968 | 0.82 | DYRK1A (0.35) | DYRK1AACSS2RPS6KA5MEN1KMT2A | |
| SCHEMBL5810298 | 0.82 | ACHE (0.48) | DYRK1AACSS2RPS6KA5HASPINMAOA | |
| Hydrochloric Acid SCHEMBL5810813 | 0.82 | KMT2A (0.37) | DYRK1AACSS2MEN1KMT2AHASPIN | |
| Hydrochloric Acid SCHEMBL5806051 | 0.81 | DYRK1A (0.34) | DYRK1AACSS2RPS6KA5ATMMAOA | |
| SCHEMBL5807292 | 0.80 | ACSS2 (0.34) | DYRK1AACSS2RPS6KA5HASPIN | |
| SCHEMBL5807191 | 0.80 | MAPT (0.48) | DYRK1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |