Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 9/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808673 | 0.86 | DYRK1A (0.44) | DYRK1AMAOAACSS2RPS6KA5HASPIN | |
| SCHEMBL5810449 | 0.85 | KMT2A (0.38) | DYRK1AACSS2HASPINDYRK2GSK3B | |
| SCHEMBL5806151 | 0.85 | MAOA (0.33) | DYRK1AMAOA | |
| Hydrochloric Acid SCHEMBL5810813 | 0.84 | KMT2A (0.37) | DYRK1AACSS2HASPINDYRK2GSK3B | |
| Hydrochloric Acid SCHEMBL5810471 | 0.84 | MAOA (0.33) | DYRK1AMAOA | |
| SCHEMBL5807487 | 0.84 | LMNA (0.38) | DYRK1AMAOAACSS2RPS6KA5HASPIN | |
| SCHEMBL5806362 | 0.84 | DYRK1A (0.46) | DYRK1AMAOAACSS2RPS6KA5HASPIN | |
| Hydrochloric Acid SCHEMBL5810379 | 0.82 | TDP1 (0.30) | — | |
| SCHEMBL5810298 | 0.81 | ACHE (0.48) | DYRK1AMAOAACSS2RPS6KA5HASPIN | |
| Hydrochloric Acid SCHEMBL5808787 | 0.81 | TRPA1 (0.43) | DYRK1AMAOAKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| EP-1697370-A1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063761-A1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-14 | — | — | WO | disclosed |