SCHEMBL5810973

SCHEMBL5810973

CC(=O)O[C@H](CCl)CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
KMT2A Q03164 3/20 0.44
RAB9A P51151 1/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
PKM P14618 1/20 0.42
MAPK1 P28482 1/20 0.42
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5810977 1.00 ALDH1A1 (0.47) ALDH1A1KMT2ARAB9AMAPTMEN1
SCHEMBL16180265 0.87 ALDH1A1 (0.48) ALDH1A1KMT2ARAB9AMAPTMEN1
SCHEMBL5796319 0.85 ALDH1A1 (0.47) ALDH1A1KMT2ARAB9AMAPTMEN1
SCHEMBL5794609 0.85 ALDH1A1 (0.47) ALDH1A1KMT2ARAB9AMAPTMEN1
SCHEMBL5795257 0.85 ALDH1A1 (0.47) ALDH1A1KMT2ARAB9AMAPTMEN1
SCHEMBL5794605 0.85 ALDH1A1 (0.47) ALDH1A1KMT2ARAB9AMAPTMEN1
SCHEMBL14830333 0.81 ALDH1A1 (0.43) ALDH1A1KMT2ARAB9AMAPTMEN1
SCHEMBL16197599 0.81 KMT2A (0.43) ALDH1A1KMT2AMAPTMEN1CA12
SCHEMBL16197875 0.81 KMT2A (0.43) ALDH1A1KMT2AMAPTMEN1CA12
SCHEMBL4821975 0.73 BACE1 (0.47) ALDH1A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013046211-A1 PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF SYMED LABS LIMITED (IN) 2013-04-04 WO disclosed
WO-2013046211-A1 PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF SYMED LABS LIMITED (IN) 2013-04-04 WO disclosed
WO-2006031179-A1 PROCESS FOR PREPARATION OF PHTALIMIDE ASTRAZENECA AB (SE) 2006-03-23 WO disclosed