Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16180265 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CA12CA9KMT2AMAPK1 | |
| SCHEMBL5810977 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CA12CA9KMT2AMAPK1 | |
| SCHEMBL5810973 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CA12CA9KMT2AMAPK1 | |
| SCHEMBL14830332 | 0.77 | USP2 (0.35) | ALDH1A1KMT2ATDP1SMN1; SMN2RAB9A | |
| SCHEMBL14830582 | 0.76 | ALOX15 (0.38) | ALDH1A1TDP1MAPT | |
| SCHEMBL14838802 | 0.73 | MTNR1A (0.38) | ALDH1A1KMT2ATDP1RAB9AMAPT | |
| SCHEMBL14830271 | 0.71 | MTNR1A (0.52) | ALDH1A1MAPT | |
| SCHEMBL14830272 | 0.71 | MTNR1A (0.52) | ALDH1A1MAPT | |
| SCHEMBL14720810 | 0.69 | USP2 (0.35) | ALDH1A1TDP1MAPT | |
| SCHEMBL29051390 | 0.69 | USP2 (0.35) | ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |