Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813290 | 0.96 | EGLN1 (0.34) | EGLN1ROCK2CXCR4 | |
| SCHEMBL5809897 | 0.86 | EGLN1 (0.35) | EGLN1ROCK2CXCR4 | |
| SCHEMBL1737813 | 0.86 | ROCK2 (0.40) | ROCK2HTR2C | |
| SCHEMBL5808251 | 0.84 | EGLN1 (0.36) | EGLN1ROCK2CXCR4 | |
| SCHEMBL5167675 | 0.82 | ELANE (0.35) | ROCK2 | |
| SCHEMBL5810493 | 0.81 | EGLN1 (0.35) | EGLN1CXCR4 | |
| SCHEMBL5810004 | 0.80 | EGLN1 (0.38) | EGLN1CXCR4 | |
| SCHEMBL5806997 | 0.79 | UGCG (0.35) | ROCK2BCHEACHE | |
| SCHEMBL5809686 | 0.78 | EGLN1 (0.39) | EGLN1ROCK2 | |
| SCHEMBL5822403 | 0.78 | EGLN1 (0.45) | EGLN1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | claimed |
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | disclosed |