Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812325 | 1.00 | P2RX3 (0.50) | P2RX3FAAHPOLBSMN1; SMN2MAPT | |
| SCHEMBL5808165 | 0.93 | P2RX3 (0.58) | P2RX3POLBSMN1; SMN2MAPTTRPV1 | |
| SCHEMBL5808159 | 0.93 | P2RX3 (0.58) | P2RX3POLBSMN1; SMN2MAPTTRPV1 | |
| SCHEMBL5812294 | 0.93 | P2RX3 (0.47) | P2RX3FAAHPOLBSMN1; SMN2MAPT | |
| SCHEMBL5812289 | 0.93 | P2RX3 (0.47) | P2RX3FAAHPOLBSMN1; SMN2MAPT | |
| SCHEMBL5796315 | 0.87 | P2RX3 (0.56) | P2RX3FAAHHDAC6 | |
| SCHEMBL5796309 | 0.87 | P2RX3 (0.56) | P2RX3FAAHHDAC6 | |
| SCHEMBL5799282 | 0.81 | HDAC3 (0.46) | FAAHTRPV1MCHR1HTR2CHDAC6 | |
| SCHEMBL5799283 | 0.81 | HDAC3 (0.46) | FAAHTRPV1MCHR1HTR2CHDAC6 | |
| SCHEMBL5806985 | 0.79 | P2RX3 (0.49) | P2RX3POLBSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245557-A1 | ELECTROCHROMIC MULTI-LAYER DEVICES WITH CHARGE SEQUESTRATION AND RELATED METHODS | Kinestral Technologies, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |
| WO-2006036881-A2 | RESORCINOL CARBONATE-BASED PHOSPHATE ESTER COMPOUNDS AS FLAME RETARDANTS | INDSPEC CHEMICAL CORPORATION (US) | 2006-04-06 | — | — | WO | disclosed |
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |